Sports Socks and Blisters
 For Calluses and Blisters, Look to Socks First: Richie  

Researchers have found that - contrary to mom's advice - you're
better off with socks made from synthetic fibers and blends, for
most activities. And the cotton-versus-synthetic conundrum is just
the beginning. Choices now include fibers engineered and blended to
keep your foot warm or cool; to hug your arches or ankles; to
protect your foot from a pounding or to slide in your shoe like a
stocking.

"It's a common misconception that socks are not important," says DR.
DOUGLAS RICHIE, a podiatrist in Seal Beach, CA who is a recognized
expert in sports socks and has researched, among other things, the
effects of cotton and acrylic fibers on feet. "They are the most
intimate layer of material against your skin," Richie says. "When
people get calluses and blisters they first blame the shoe, when
they should be looking at the sock."

Source: Janet Cromley, Los Angeles Times [5/1/06]